Growth Hormone AxisResearch OnlyNot For Human Consumption

CJC-1295

DAC:GRF · Drug Affinity Complex: Growth Hormone Releasing Factor

A long-acting growth hormone releaser, one injection keeps your pituitary gland producing growth hormone for up to a week.

MECHANISM OF ACTION

CJC-1295 is a modified version of the signal your brain normally sends to the pituitary gland (a pea-sized gland at the base of the brain) telling it to release growth hormone. The natural signal only lasts about 30 minutes before it breaks down. CJC-1295 is engineered to grab onto albumin (a common protein in your blood) once injected, which protects it from breaking down. This extends its activity from 30 minutes to roughly 6–8 days per injection. Your pituitary then releases growth hormone in pulses, the same natural pattern, raising both growth hormone and IGF-1 (a growth factor that supports muscle and recovery). Unlike injecting growth hormone directly, this keeps the body's own feedback system intact.

RESEARCH APPLICATIONS

  • GH secretagogue research and pituitary axis modelling
  • Body composition - lean mass accretion and adipose reduction
  • IGF-1 axis stimulation research
  • Age-related GH decline (somatopause) models
  • Synergistic stacks with GHRP agents (Ipamorelin)

RESEARCH HIGHLIGHTS

Extended GH and IGF-1 Elevation

2006

Research reported that a single administration produced an extended growth hormone peak lasting several days, with proportional IGF-1 increases.

Ref: Teichman et al., JCEM

Sustained IGF-1 Response

2009

Twice-weekly administration maintained IGF-1 elevation above baseline for 14+ days with no tachyphylaxis over 6-week study periods.

Ref: Ionescu et al., Growth Horm IGF Res

RESEARCH PROTOCOL NOTES

CombinationStacked with Ipamorelin (GHRP) for synergistic GH pulse amplification - Growth Matrix Stack
Physical formSupplied lyophilised (freeze-dried powder) unless stated otherwise
ReconstitutionBacteriostatic water; swirl gently, do not shake

Chemical Identity

Molecular FormulaC165H269N47O46
Molecular Weight3647.1 g/mol
CAS Number863288-34-0
SolubilitySoluble in bacteriostatic water

Storage & Stability

Lyophilised: 2–8°C or -20°C. Reconstituted: 2–8°C, 21–28 days. Avoid room temperature.

Regulatory Status

No regulatory approval. WADA prohibited (S2). SAHPRA: import authorisation required for research.

Important - read before proceeding

This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.

Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.