Research Compendium/KPV
Recovery & RepairResearch OnlyNot For Human Consumption

KPV

Lys-Pro-Val · Alpha-MSH tripeptide C-terminus · KPV/KLOW Stack

A three-amino-acid fragment of a larger natural peptide, studied in laboratory research on inflammatory signalling pathways.

MECHANISM OF ACTION

KPV is one of the smallest peptides studied for inflammation, just three amino acids (building blocks) linked together. It comes from a larger hormone your body already makes. Despite its tiny size, it powerfully switches off the signals that cause inflammation inside cells. What makes it interesting is that it works especially well in the gut: when taken orally, it gets absorbed directly through the intestinal lining and acts locally where it lands. KLOW is a related compound often paired with KPV to cover a broader range of inflammation pathways.

RESEARCH APPLICATIONS

  • NF-κB signalling pathway research
  • Mucosal barrier research models
  • Melanocortin fragment pharmacology
  • Combination research with tissue-repair peptides

RESEARCH HIGHLIGHTS

NF-κB pathway activity

2010

Laboratory studies describe the fragment interacting with NF-κB signalling, which is the mechanism researchers use to explain its behaviour in inflammation models. Research observations only.

Ref: Laroui et al., Gastroenterology

RESEARCH PROTOCOL NOTES

Stack contextOften combined with KLOW for broader anti-inflammatory coverage
Available formatsVial, Pen (KPV/KLOW Stack)
Physical formSupplied lyophilised (freeze-dried powder) unless stated otherwise

Chemical Identity

Molecular FormulaC15H28N4O4
Molecular Weight328.4 g/mol
CAS Number63958-90-7
SolubilityHighly soluble in water

Sequence

Lys-Pro-Val

Storage & Stability

Lyophilised: -20°C. Reconstituted: 2–8°C, use within 14 days. Small tripeptide - less stable in solution than larger peptides.

Regulatory Status

Unscheduled in South Africa. Supplied for laboratory and research use only. Not a registered medicine, not evaluated by SAHPRA, not for human consumption. Not WADA listed.

Important - read before proceeding

This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.

Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.

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