MECHANISM OF ACTION
NAD⁺ is a molecule found in every single cell in your body. It acts like a rechargeable battery, it picks up energy from food and delivers it to the cell's power plants (mitochondria). Beyond energy, it also feeds the proteins responsible for repairing damaged DNA and those linked to living longer (called sirtuins). The catch: your NAD⁺ levels drop roughly 50% for every decade of life after your 20s. This is linked to slower energy, reduced DNA repair, and general ageing effects. Oral supplements like NMN or NR are converted into NAD⁺ by the body, a slower process. Injectable NAD⁺ bypasses that conversion and raises levels in the bloodstream directly and fast.
RESEARCH APPLICATIONS
- Mitochondrial bioenergetics restoration
- Sirtuin activation (SIRT1/3 longevity pathway)
- DNA repair enhancement (PARP substrate)
- Cellular energy metabolism and mitochondrial function research
- Cognitive clarity and neurological function research
RESEARCH HIGHLIGHTS
Sirtuin Activation and Longevity
2013NAD⁺ repletion in aged preclinical subjects activated SIRT1 and SIRT3, restoring mitochondrial function, improving muscle endurance, and extending healthspan in multiple studies.
Ref: Gomes et al., Cell
DNA Repair via PARP
2016NAD⁺ depletion impairs PARP-mediated DNA repair; repletion restores repair capacity - particularly relevant in age-related genomic instability models.
Ref: Fang et al., Cell Metabolism
RESEARCH PROTOCOL NOTES
Chemical Identity
Storage & Stability
Lyophilised: 2–8°C, 12–24 months. Reconstituted: use within 24–48 hours at 2–8°C. Highly sensitive to light and oxidation - use amber vials, protect from air.
Regulatory Status
Not a registered pharmaceutical. Injectable vials supplied as research compound only. Not WADA prohibited.
Important - read before proceeding
This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.
Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.